Ghamar-ol-molouk Vaziri, the most famous female vocalist of Persian contemporary music, was born around 1903 in the city of Ghazvin. She lost her parents in childhood and was raised by her grandmother, Mulla-Kheyr-al-Nesa (titled to Eftekhar-al-Zakerin) who was a singer of the Rozekhani ceremonies (religious ceremony). Following her grandmother to this ceremonies, Ghamar made her first acquaintance with the Persian vocal music of the Rozekhani genre.

When Ghamar's grandmother went to Karbala on pilgrimage of Imam Hossein's shrine; she moved to the house of her cousin were musical gatherings were regularly arranged and great masters of Persian music such as Darvish Khan (tar and setar master), Rokn-al-Din Khan Mokhtari (violin master), Haji Khan Eyn-al-Doleh (tonbak master) and Shah-zadeh Hesam-al-Saltaneh (multi-instrumentalist) were playing.

Ghamar met Ostad Morteza Neydavoud for the first time in a wedding ceremony where the master heard her singing and invited her to attend in his class in order to learn the radif repertoire of Persian music.

As the most talented vocalist artist trained by Ostad Neydavoud she soon became one of the best singers of Iran. Their first concert was given at the salon of the Grand Hotel about 1924 when she as a female performer appeared in public without wearing the traditional veil. Among her other teachers were Aref Ghazvini, Mohammad Ali Amir Jahed, Habib Samaei, Abol Hassan Saba and Arsalan Dargahi, all of them the most respected musical artists of their time.

Ghamar was the first prominent female Iranian artist who during a turbulent time of social and political upheaval presented patriotic and feminist songs reflecting the struggle of the Iranian people for freedom and expressing the efforts of the Iranian woman for equality.

What Ghamar earned as a popular artist of the Iranian people, she shared among the poors. Being involved in many charity activities during her carrier she gave many concerts in favor of poor people and beggars of Tehran. She, herself, passed away in poverty on 5th of August 1959.